The Kolbe-Schmitt reaction is an organic reaction used to convert a phenol to a hydroxy benzoic acid using carbon dioxide gas, a base, and acid work-up. The Kolbe-Schmitt reaction has been a standard procedure for the preparation of the Kolbe-Schmitt reaction in the form of a general survey. Special emphasis. PDF | On Oct 2, , Zoran Markovic and others published Mechanism of the Kolbe—Schmitt Reaction. Structure of the Intermediate.

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The compound is also found in Ganoderma lucidum, a medicinal mushroom with the longest record of use. Adolph Wilhelm Hermann Kolbe 27 September — 25 November [1] was a seminal contributor in the birth of modern organic chemistry.

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Kolbe–Schmitt reaction | Revolvy

Levy, G; Tsuchiya, T Natural sources include volcanoes, hot springs and geysers, and it is freed from carbonate rocks by dissolution in water and acids. Member feedback about Sodium phenoxide: Annalen der Chemie und Pharmacie.

In Germany, the frequency of the surname was higher than national average 1: He received his Abitur in and entered the University of Marburg the same year.


The Kolbe—Schmitt reaction proceeds via the nucleophile addition of a phenoxide, classically sodium phenoxide NaOCHto carbon dioxide to give the salicylate. Non-steroidal anti-inflammatory drugs Revolvy Brain revolvybrain. Parabens are effective preservatives in many types of formulas.

The final step is reaction of the salicylate with acid to form the desire Gentisic acid topic Gentisic acid is a dihydroxybenzoic acid. Gentisic acid is a dihydroxybenzoic acid.

Hermann Kolbe Rudolf Schmitt. He moved several times during his childhood and entered the Gymnasium as boarding pupil in Marburg.

Kolbe-Schmitt reaction ~

Schmitt is a German surname. Formylation reactions Revolvy Brain revolvybrain.

Member feedback about Rudolf Schmitt: Member feedback about Carboxylation: According to his contemporary Jerome, Augustine “established anew the ancient Faith”.

Member feedback about Carboxylic acid: Some of the most important electrophilic aromatic substitutions are aromatic nitration, aromatic halogenation, aromatic sulfonation, and acylation and alkylating Friedel—Crafts reaction.

Salicylate decarboxylase topic Salicylate kolbee EC 4. Member feedback about Salicylate decarboxylase: Hydroxy acids Revolvy Brain revolvybrain.

Kolbe–Schmitt reaction

Functional groups Revolvy Brain revolvybrain. Heat processes Flash smelting — a refinement on smelting, for sulfur-containing ores produces copper, nickel and lead Electrolysis The availability of e Member feedback about 3-Hydroxynaphthoic acid: It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone.


The regiochemistry of the carboxylation in this case is sensitive to temperature.

Carboxylation topic Carboxylation is a chemical reaction in which a carboxylic acid group is produced by resction a substrate with carbon dioxide. The Kolbe—Schmitt reaction proceeds via the nucleophile addition of a phenoxide, classically sodium phenoxide NaOC 6 H 5to carbon dioxide to give the salicylate.

It has been prolific in the foundation of schools, universities and hospitals, and many clergy have been active in the sciences.

Ullmann’s Encyclopedia of Industrial Chemistry. It is one of the several carboxylic acids derived from 2-naphthol. The salts and esters of salicylic acid are known as salicylates. Salts and esters of carboxylic acids are called carboxylates. Retrieved from ” https: Member feedback about Scientific phenomena named after people: Greenhouse gases Revolvy Brain revolvybrain.

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