Klaricid IV mg (PL /, Abbott Laboratories Ltd). No new or unexpected safety concerns arose from this application and it was therefore judged that. Indications, side effects, contraindications and other prescribing information for Klaricid IV on MIMS. Clarithromycin is indicated in: Lower respiratory tract infection: acute and chronic bronchitis and pneumonia;; Upper respiratory tract infection: sinusitis and.
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Klaricid IV | MIMS online
It is recommended that patients who experience tablet residue in the stool and no improvement in their condition should be switched to a different if formulation e. There is a risk of serious haemorrhage and significant elevations in International Normalized Ratio INR and prothrombin time when clarithromycin is co-administered with warfarin see section 4.
Packages and Strengths Klaricid Iv Injection is available in the following packages and strengths. The most klaircid and common adverse reactions related to clarithromycin therapy for both adult and peadiatric populations are abdominal pain, diarrhoea, nausea, vomiting and taste perversion.
To view klaricdi changes to a medicine you must sign up and log in. Last updated on eMC: How to store Klaricid IV Keep out of the sight and reach of children Do not use after the expiry date on the carton klarixid vial.
With oral use in adults. Children under 12 years should not be given Klaricid IV. The use of the following drugs is strictly contraindicated due to the potential for severe drug interaction effects: Caution is advised regarding concomitant administration of clarithromycin and triazolobenzodiazepines, such as triazolam, and intravenous or oromucosal midazolam see section 4. Products Type IV Injection. Throat and sinus infections 3.
Always consult your healthcare provider to ensure the information jlaricid on this page applies to your personal circumstances.
There have been rare reports of clarithromycin ER tablets in the stool, many of which have occurred in klaricif with anatomic including ileostomy or colostomy or functional gastrointestinal disorders with shortened GI transit times.
To email a medicine you must sign up and log in. Clarithromycin has bactericidal activity against several bacterial strains. You can also report side effects directly via the Yellow Card Scheme at: Consideration should be given to official guidance on the appropriate use of antibacterial agents.
The most frequent and common adverse reactions related to clarithromycin therapy for both adult and peadiatric populations are abdominal pain, diarrhoea, nausea, vomiting and taste perversion. The hydroxy metabolite of clarithromycin, a product of parent drug metabolism also has anti-microbial activity. Patients receiving terfenadine who have pre-existing cardiac abnormalities or electrolyte disturbances.
When midazolam was co-administered with clarithromycin tablets mg twice dailymidazolam AUC was increased 2. Klariccid inhibits the intracellular protein synthesis of susceptible bacteria. Consideration of these findings should be balanced with treatment benefits when prescribing clarithromycin.
Drugs interacting by similar kkaricid through other isozymes within the cytochrome P system include phenytoin, theophylline and valproate. Some patients may have had pre-existing hepatic disease or may have been taking other hepatotoxic medicinal products.
,laricid potential for dizziness, vertigo, confusion and disorientation, which may occur with the medication, should be taken into account before patients drive or use machines.
Clarithromycin mg tablets Clarithromycin mg tablets. This leaflet was last revised in February Therefore, as the following situations may lead to an increased risk for ventricular arrhythmias including torsades de pointesclarithromycin should be used with caution in the following patients.
Klaricid I.V 500 mg Clarithromycin Lactobionate For Injection, Packaging Type: Vial
When saquinavir is co-administered with ritonavir, consideration should be given to the potential effects of ritonavir on clarithromycin see section 4. Continue typing to refine.
Acute hypersensitivity reactions Clostridium difficile associated diarrhea Development of drug resistant bacteria Exacerbation of Myasthenia Gravis Hepatotoxicity QT prolongation. Enter medicine name or company Start typing to retrieve search suggestions.
Store in the original container as the powder is sensitive to light. Saquinavir Both clarithromycin and saquinavir are substrates and inhibitors of CYP3A, and there is evidence of a bi-directional drug interaction. Observations from drug interaction studies using the soft gelatin capsule formulation may not be representative of the effects seen using the saquinavir hard gelatin capsule.
Klaricid IV mg (SmPC) – Summary of Product Characteristics (SmPC) – (eMC)
If treatment with clarithromycin cannot be avoided, therapy with lovastatin or simvastatin must be suspended during the course of treatment. In some of the reports of rhabdomyolysis, clarithromycin was administered concomitantly with statins, fibrates, colchicine or allopurinol see section 4.
Hepatic failure, jaundice hepatocellular. Monitoring the patient for increased Kkaricid pharmacological effects is suggested. Skin and soft tissue infections of mild to moderate severity: Klabid Er mg 7pcs.
To be on the safe side, it is important not to use expired drug. Clarithromycin acts by inhibiting microsomal protein synthesis in susceptible organisms mainly by binding to the donor site on the 50S sub- unit of the bacterial ribosome and preventing translocation to that site. If you are given more Klaricid IV than you should have As Klaricid IV is given to you by a doctor, an overdose is unlikely but symptoms may include vomiting and stomach pains.
Method of administration Refer to the summary of product characteristics for posology information.
Sildenafil, tadalafil and vardenafil Each of these phosphodiesterase inhibitors is metabolised, at least in part, by CYP3A, and CYP3A may be inhibited by concomitantly administered clarithromycin. How to store Klaricid IV Keep out of the sight and reach of children Do not use after the expiry date on the carton and vial.
Clostridium difficile- associated diarrhoea CDAD has been reported with use of nearly all antibacterial agents including clarithromycin, and may range in severity from mild diarrhoea to fatal colitis.